HRT Guide 2026: What's Changed and What You Need to Know

New NICE guidelines have updated recommendations for hormone replacement therapy in 2026. The biggest changes: transdermal estrogen is now preferred over oral, body-identical progesterone is the recommended progestogen, and there is no upper age limit for starting or continuing HRT when benefits outweigh risks. The guidelines also emphasise personalised dosing and shared decision-making. Talk to your GP about whether the new guidance changes anything for you.